Suli Pharmaceutical Technology Jiangyin Co., Ltd.
APIs’ Intermediates
NO. Product name CAS No. Molecular formula
Intermediates of Ledipasvir

(S)-tert-butyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-iMidazol-2-yl) -5-azaspiro[2.4]heptane-5-carboxylate

1441670-89-8

C27H26BrF2N3O2

N-[(1S)-1-[[(6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]carbonyl]-2-methylpropyl]carbamic acid methyl ester

1256388-50-7
Intermediates of Daclatasvir

1H-Imidazole, 5,5’-[1,1’-biphenyl]-4,4’-diylbis[2-(2S)-2-pyrrolidinyl-, hydrochloride (1:4)

1009119-83-8

C26H32Cl4N6

4,4'-Bis(2-bromoacetyl)biphenyl

4072-67-7

C16H12Br2O2

N,N'-[[1,1'-Biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]biscarbamic acid dimethyl ester hydrochloride

1009119-65-6
Intermediates of Tofacitinib

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

3680-69-1

C6H4ClN3

(3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride

1062580-52-2

C14H24Cl2N2·2(HCl)

(2R,3R)-2,3-bis[(4-methylbenzoyl)oxy] butanedioic acid compd. with (3R,4R)-N,4- dimethyl-1-(phenylmethyl)-3-piperidinamine

477600-71-8
Intermediates of Fondaparinux sodium

Methyl 6-o-acetyl-3-o-benzyl-2-benzyloxycarbonylamino- 2-deoxy- a-d-glucopyranose

114869-95-3

C24H29NO8

Intermediate of Indacaterol

2-Aminoindan hydrochloride

2338-18-3

C9H12ClN

Velpatasvir intermediates

4-Bromo-n-methoxy-n,3-dimethylbenzamide

170230-01-0

C10H12BrNO2

9-Bromo-3-(2-bromoacetyl)-10,11-dihydro-5H-benzo[d]naphtho[2,3-b]pyran-8(9H)-one

1438383-89-1

C19H14Br2O3

Carbamic acid, N-[(1R)-2-[(2S,4S)-2-[4-[1,11-dihydro-2-[(2S,5S)-1- [(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H

1377049-84-7

C49H54N8O8

(2S,4S)-2-[5-[1,11-Dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxym

1378391-45-7

(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid

1378388-16-9
Tamsulosin intermediates

2-(2-Ethoxyphenoxy)ethyl bromide

3259-03-8

C10H13BrO2

R-(-)-5-(2-amino-propyl)-2-methoxy-benzenesulfonamide

112101-81-2

C10H13NO4S

Intermediates of Lenalidomide

Methyl 2-bromomethyl-3-nitrobenzoate

98475-07-1

C9H8BrNO4

Ribociclib’s intermediates

Ribociclib Succinate

1374639-75-4

2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

1211443-61-6

4-​[6-​[[7-​cyclopentyl-​6-​[(dimethylamino)​carbonyl]​-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​2-​yl]​amino]​-​3-​pyridinyl]​-​1-​Piperazinecarboxylic acid 1,​1-​dimethylethyl ester

1374639-78-7

2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid

1211443-58-1

Ribociclib base

1211441-98-3

(2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol

1374639-77-6
Abemaciclib’s Intermediates

4-​[6-​[[7-​cyclopentyl-​6-​[(dimethylamino)​carbonyl]​-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​2-​yl]​amino]​-​3-​pyridinyl]​-​1-​Piperazinecarboxylic acid 1,​1-​dimethylethyl ester

1231930-37-2

5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-amine

1180132-17-5

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

1231930-33-8

6-(2-chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

1231930-42-9
Sacubitril-Valsartan (LCZ696)’s intermediates

Sacubitril-Valsartan (LCZ696)

936623-90-4

(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

1012341-50-2

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride

149690-12-0

(alphaR,gammaS)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester calcium salt (2:1)

1369773-39-6
Roxadustat and Intermediates

4-Hydroxy-7-phenoxy-3-isoquinolinecarboxyli c acid methyl ester

1455091-10-7

1-Methyl-4-hydroxy-7-phenoxy isoquinoline-3-methyl formate

1421312-34-6

4-​Phenoxy-​1,​2-​benzenedicarboxylic acid

37951-15-8

5-phenoxyisobenzofuran-1(3H)-one

57830-14-5

C14H10O3

Ethyl 1,4-dihydroxy-7-phenoxyisoquinoline-3-carboxylate

Ethyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate

4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid ethyl ester

1809286-36-9
Intermediates of Acalabrutinib

(3-Chloropyrazin-2-yl) Methanamine hydrochloride

939412-86-9

C5H7Cl2N3

(2S)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-Pyrrolidinecarboxylic acid phenylmethyl ester

1420478-88-1

[4-[(Pyridin-2-yl)carbamoyl]phenyl]boronic acid

850568-25-1

C12H11BN2O3

N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide

1383385-64-5

(S)-benzyl 2-((3-chloropyrazin-2-yl)methylcarbamoyl)pyrrolidine-1-carboxylate

1418307-17-1

4-[8-amino-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-Benzamide

1420478-90-5
Elagolix and Its Intermediates

Elagolix Sodium

832720-36-2

C32H29F5N3NaO5

N-​[[2-​Fluoro-​6-​(trifluoromethyl)​phenyl]​methyl]​urea

830346-46-8

C9H8F4N2O

2-Fluoro-3-methoxybenzeneboronic acid

352303-67-4

C7H8BFO3

1-(2-Fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H- pyrimidine-2,4-dione

830346-47-9

C13H10F4N2O2

5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione

830346-48-0

C13H9BrF4N2O2

1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione

1150560-54-5

5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione

1150560-59-0
Intermediates of Lorlatinib

(12aR)​-7-​(hexyloxy)​-​3,​4,​12,​12a-​tetrahydro-1H-​[1,​4]​Oxazino[3,​4-​c]​pyrido[2,​1-​f]​[1,​2,​4]​triazine-​6,​8-​dione Tosylate

1803573-19-4

2-(bis(tert-butoxycarbonyl)amino)-5-bromopyridin-3-yl4-methylbenzenesulfonate

1803573-21-8

1-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrilehydrochloridesalt

1643141-20-1
Upadacitinib and Its Intermediates

Upadacitinib

1310726-60-3

2-​bromo-5H-​Pyrrolo[2,​3-​b]​pyrazine

875781-43-4

2-​Bromo-​5-​[(4-​methylphenyl)​sulfonyl]​-​5H-​pyrrolo[2,​3-​b]​pyrazine

1201186-54-0

N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid ethyl ester

1869118-24-0

(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid Dicyclohexylamine Salt

2095311-49-0

(3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester

1428243-26-8

Tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo [2,3-b]pyrazin-2-yl)carbamate

1201187-44-1

8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-3H-Imidazo[1,2-A]pyrrolo[2,3-E]pyrazine hydrochloride (1:2)

2050038-84-9

(3R,4S)-4-Ethyl-1,3-pyrrolidinedicarboxylic acid 1-(phenylmethyl) ester (alphaR)-alpha-methyl-1-naphthalenemethanamine

1428243-25-7

(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid

1428243-24-6
Darolutamide and Intermediates

Darolutamide

1297538-32-9

2-chloro-4-(1H-pyrazol-3-yl)benzonitrile

1297537-37-1

(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile

1297537-41-7

5-acetyl-1H-pyrazole-3-carboxylic acid

1297537-45-1

(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide

1297537-33-7

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